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By Carl Thompson
December 5, 2020

P6 Extreme Black

With the bold description “legendary anabolic agent” on its label, P6 Extreme Black returns after temporarily leaving the market.

Cellucor, P6 Extreme Black’s manufacturer, promises it boosts testosterone and gives more energy than any other testosterone booster legally available.

But P6 Extreme Black faces a different market than it left. Can it stand its ground against today’s testosterone boosters?

The P6 Extreme Black Formula

P6 Extreme Black packs 15 different ingredients into its formula to stimulate testosterone production, muscle growth, and mental stimulation. The first seven ingredients are the following:

Vitamin D (3332 iu) is a fat-soluble vitamin. In a 2011 clinical study, researchers found vitamin D significantly increases testosterone production.[1]

Vitamin B6 (2 mg) regulates androgen production.[2] Many people believe higher vitamin B6 amounts result in greater testosterone production, but clinical studies have yet to confirm this theory.

Zinc (30 mg) is an essential mineral. Studies show zinc supplements significantly raises plasma testosterone levels.[3]

Copper (2 mg) is a crucial trace mineral for a healthy metabolism.[4] It also appears to positively affect testosterone production, but more research is needed.

D-aspartic acid magnesium chelate is an amino acid that plays a role in hormone production and release. In a 2009 study, researchers discovered DAA boosts testosterone production in rats.[5] Its effect on humans is unclear, however.

D-serine is an amino acid that facilitates transmission and synaptic plasticity in rats’ central nervous system.[6] D-serine is believed to serve the same ligand function in human central nervous systems, but clinical trials still need to be conducted

Zinc monomethionine provides the same testosterone boosting benefits as normal zinc. This form facilitates absorption.

I like the various vitamins and minerals that appear to boost testosterone production. Other than first four listed ingredients, however, individual ingredient dosages are not listed. This makes it difficult to tell if the total formula actually works.

Is It Safe?

While vitamin dosages are within tolerable upper intake levels, they could still cause side effects. For example, the high zinc concentrations cause nausea, stomach damage, and even leave a metallic taste.

How Do You Use P6 Extreme Black?

For best results, take 1 serving (3 capsules) 30 minutes before you work out. Then on non-workout days, take 1 serving with your first meal.
Experienced users can gradually increase the dosage to 6 capsules a day.

How Much Does It Cost?

P6 Extreme Black just hit the market and many vendors have yet to start selling it. However, I was able to find it at GNC.com for $89.99 for one bottle (90 capsules). I expect most vendors will sell P6 Extreme Black for $80 to $100.

Final Thoughts on P6 Extreme Black

While P6 Extreme Black provides some impressive ingredients, I can’t recommend the product. Since P6 Extreme Black is so new, there are no user reviews and I can’t tell if it’s effective and safe. $100 is a lot of money to spend on an unproven testosterone booster.

In the future, P6 Extreme Black may be a worthwhile investment but right now it’s a risky buy.


[1] Pilz, S., et al. “Effect of vitamin D supplementation on testosterone levels in men.” Hormone and Metabolic Research, 43.03 (2010): 223-225. http://www.ncbi.nlm.nih.gov/pubmed/21154195

[2] Allgood, Victoria E., and J. A. Cidlowski. “Vitamin B6 modulates transcriptional activation by multiple members of the steroid hormone receptor superfamily.” Journal of Biological Chemistry, 267.6 (1992): 3819-3824. http://www.jbc.org/content/267/6/3819.short

[3] For example, Netter, A., K. Nahoul, and R. Hartoma. “Effect of zinc administration on plasma testosterone, dihydrotestosterone, and sperm count.” Systems Biology in Reproductive Medicine, 7.1 (1981): 69-73. Effect of zinc administration on plasma testosterone

[4] University of Maryland Medical Center. “Copper.” Accessed 4.18.2013. http://www.umm.edu/altmed/articles/copper-000296.htm

[5 ] Topo, Enza, et al. “The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats.” Reprod Biol Endocrinol, 7 (2009): 120. http://www.biomedcentral.com/content/pdf/1477-7827-7-120.pdfStudien

[6] Panatier, Aude, et al. “Glia-derived D-serine controls NMDA receptor activity and synaptic memory.” Cell, 125.4 (2006): 775-784. http://www.sciencedirect.com/science/article/pii/S009286740600506X

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