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By Carl Thompson
December 5, 2020

Panthera Primal Test

Panthera Primal Test

“Panthera was and remains the first company in the world to introduce LJ100 into a sports nutrition product,” claims Panthera’s president. LJ100 — a powerful long jack extract — is the key ingredient in Panthera Primal Test.

The president goes on to claim LJ100 boosted testosterone levels in every study participant who used it.

Very few testosterone-boosting ingredients are that effective, so I was curious to see what research the manufacturer used…

Are the Ingredients Effective?

“The ingredients we select are validated for efficacy in clinical trials which match pharmaceutical clinical trial standards,” says PantheraLabs.com. It also says long jack extract boosted testosterone for every participant in not 1, but 7 human studies!

If these claims are true, Panthera Primal Test has the potential to be very effective. Naturally, I expected the company would provide the research to back up their claims, but they did not.

On my own, I found one human study involving long jack extract, but not 7 studies and not studies with results like the website describes.

Long jack extract (200 mg), also known as eurycoma longifolia, contains substances that elevate testosterone, enhance libido, and inhibit SHBG. Men with low testosterone took 200 mg long jack extract for 30 days. Whereas 35% had normal testosterone levels before the study, 90% had normal testosterone after the study.[1]

L-arginine HCL (1000 mg) is the precursor to nitric oxide.[2] A chemical messenger, nitric oxide mainly increases blood flow. It does this by relaxing and widening blood vessels. L-arginine HCL has no impact on testosterone, but increased blood flow helps muscles repair and receive nutrients faster.

Niacinamide (50 mg) comes from vitamin B3, as does niacin. But niacin lowers cholesterol and increases blood flow, and niacinamide does not. It’s mainly used in skincare products or to treat vitamin B3 deficiency. I’m not sure what purpose it serves in Panthera Primal Test.

Safety Concerns and Side Effects

People with allergies or asthma should be careful about using L-arginine because it may aggravate these conditions. L-arginine may lower blood pressure too, which could cause problems if you already have low blood pressure.

Niacinamide may enhance allergy symptoms because it releases histamine. It could also lower blood pressure and increase blood sugar. People with diabetes should exercise caution when using niacinamide.

L-arginine and niacinamide might cause these side effects:

• Abdominal pain
• Bloating
• Diarrhea
• Flatulence
• Sweating
• Dizziness

Researchers haven’t tested long jack extract enough to know if it’s completely safe for human consumption.

How to Get the Best Results

Take 1 serving (2 capsules) daily to get the proven dosage for long jack extract. The manufacturer suggests taking Panthera Primal Test right before going to bed. However, these ingredients are beneficial throughout the day.

For best results, take the capsules in the morning, before a meal, before a workout, or before bedtime. Just make sure to take it on an empty stomach and drink a large glass of water.

Long jack extract boosts testosterone and L-arginine HCL increases blood flow. However, you must eat a healthy diet and exercise regularly to build muscle or burn fat.

Where to Buy Panthera Primal Test

Panthera Pharmaceuticals’ products are often sold in The Vitamin Shoppe and GNC stores. But it seems Panthera Primal Test is only sold online. These prices are for a bottle that lasts 30 days when used as directed:

• $49.95 per bottle
• Shipping costs $3.95
• Orders over $100 ship free

• $30.49 per bottle
• Standard shipping starts at $5.95
• Delivery takes 1-5 business days

• $39.95 per bottle
• Cost for standard shipping starts at $5.98
• Delivery takes 3-5 business days

AllStarHealth.com not only has the best price, it also has the best return policy. Used and unused products can be returned within 30 days for a full refund. Used products must have at least 25% of the content. So, the Panthera Primal Test bottle should have no less than 15 capsules.

PantheraLabs.com doesn’t describe a return policy. If you have questions about a return, contact customer service to see if you qualify. The phone number is 855-777-4625.

Bodybuilding.com takes back used and unused products, but only unused products receive a refund. In most cases, used products can be exchanged for store credit or a replacement.

About Panthera Pharmaceuticals

The company was found in 2007 by Mark Rustad, who is currently the president. The headquarters is located in New York at this address:

11 Lincoln St.
Copiague, NY 11726-1530

“I personally formulate every product manufactured and sold by our company,” said Rustad, on the website’s About Us page. Rustad graduated from Cornell University where he studied Chinese Herbal Pharmacopia. In 1983, he received a master’s degree in East Asian Studies.

I’m not sure how this educational background qualifies Rustad to formulate supplements, but he explains, “My partners, Asha and Jitendra Patel and our associate Chetan–all biochemists with advanced degrees–review, advise and often lend suggestions which improve my original concepts.”

Panthera Pharmaceuticals is a well-known company, but I don’t know how reliable and respected they are. I was unable to find feedback, complaints, or a Better Business Bureau listing.


I was very disappointed that the company makes several significant claims, but doesn’t provide any supporting evidence. I found one study proving long jack extract boosts testosterone, but more research is needed. At this point, medical professionals have no idea how safe long jack extract is.

Panthera Primal Test has strong dosages for long jack extract, L-arginine HCL, and niacinamide. Long jack extract is the only testosterone-boosting ingredient, but L-arginine HCL may increase blood flow, which is beneficial.

Panthera Primal Test may be an effective testosterone supplement. However, I’m hesitant to recommend a product coming from a company that makes unsupported claims. It makes me doubt their reliability. I suggest you keep looking.


[1] Tambi, M, M Imran, and R Henkel. “Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism?” Andrologia. 44. (2012): 226-30.

[2] Andrew, PJ, and B Mayer. “Enzymatic function of nitric oxide synthases.” Cardiovascular Research. 43.3 (1999): 521-31.

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